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The Science and Medicine
of Sepsis Management

WebCAST

Webcast CME Disclosure

Please read this notice and click the acknowledgement
at the bottom of the page to continue.

Release Date:

March 30, 2010

Expiration Date:

March 30, 2012

Intended Audience:

This activity has been designed to meet the educational needs of all critical care physicians, emergency medicine specialists, nurses, pharmacists, respiratory therapists and other involved in the care of critically ill patients in the intensive care of emergency medicine setting.

Statement of Need/Program Overview

The educational need for this program is to educate critical care specialists, emergency physicians and related specialties about pharmacologic, drug selection, cost-related, and risk assessment issues related to severe sepsis in the critical care environment, an issue which has been highlighted by guidelines issued by organizations and professional associations specializing in critical care and emergency medicine.

Registration:

Participation in this WebCAST is complimentary, and clinicians are invited to view this CME-certified program and/or share this invitation with other colleagues, departmental staff members, and healthcare professionals.

Grantor Support:

Boehringer IngelheimSupported by an independent
educational grant
from Eisai, Inc.

Accreditation Statement:

This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of Postgraduate Institute for Medicine (PIM) and CMEducation Resources, LLC. PIM is accredited by the ACCME to provide continuing medical education for physicians.

Credit Designation Statement:

Postgraduate Institute for Medicine designates this educational activity for a maximum of 1.5 AMA PRA Category 1 Credit(s)™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Policy on Faculty & Provider Disclosure:

Postgraduate Institute for Medicine (PIM) requires instructors, planners, managers and other individuals who are in a position to control the content of this activity to disclose any real or apparent conflict of interest they may have as related to the content of this activity. All identified conflicts of interest are thoroughly vetted by PIM for fair balance, scientific objectivity of studies mentioned in the materials or used as the basis for content, and appropriateness of patient care recommendations.

Educational Objectives

At the end of this session, participants should be able to:

  • Describe the prognostic factors that determine clinical outcomes of patient with severe sepsis
  • Describe the epidemiology and causative factors of sepsis
  • Identify the potential pathophysiological and clinical impact of modulating TLR-derived signals in order to mitigate adverse effects of immune responses observed in septic shock syndrome
  • Discuss emerging strategies for improving patient care and clinical outcomes for severe sepsis syndrome
  • Analyze evolving strategies for improving outcomes in sepsis that are focused on suitable targets for interrupting the inflammatory cascade

Program Faculty and Disclosures:

The faculty reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this CME activity:

Steven M. Opal, MD
Professor of Medicine
The Warren Alpert School of Medicine of Brown University
Chief, Infectious Disease Division,
Memorial Hospital of Rhode Island
Providence, RI

Research Support: Inimex, Sirtris, Eisai, Atoxbio

Jean-Paul Mira, MD, PhD
Professor of Critical Care Medicine
Chair, Medical Intensive Care Unit
Head, Variability of Innate Immunity Research Laboratory
Cochin-St.Vincent dePaul University Hospital
Paris, France

Consultant: Eli Lilly; LFB; EISAI
Advisory Boards: EISAI; LFB
Honoraria: Eli Lilly, LFB, Novartis, MSD, BRAHMS



Dr. Pierre-Francois Laterre, MD
Professor of Critical Care
St Luc University Hospital
Universite Catholique de Louvain
Brussels, Belgium

Nothing to disclose


The planners and managers reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this CME activity:

The following PIM planners and managers Jan Hixon, RN, BSN, MA, Trace Hutchison, PharmD, Julia Kimball, RN, BSN, Samantha Mattiucci, PharmD and Jan Schultz, RN, MSN, CCMEP hereby state that they or their spouse/life partner do not have any financial relationships or relationships to products or devices with any commercial interest related to the content of this activity of any amount during the past 12 months.

The following CMEducation Resources planner and manager: Gideon Bosker, hereby states that he or his spouse/life partner do not have any financial relationships or relationships to products or devices with any commercial interest related to the content of this activity of any amount during the past 12 months.

Disclosure of Unlabeled Use:

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. Postgraduate Institute for Medicine (PIM), CMEducation Resources and Eisai, Inc. do not recommend the use of any agent outside of the labeled indications.

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of PIM, CMEducation Resources and Eisai, Inc. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

Hardware and Software Requirements:

To participate in this program, viewers must have a PC or Macintosh computer that has active, ongoing internet access for the duration of the program, as well as a compatible Flash-viewer. An email address is required for registration, and a printer is required to printout the CME certificate.

Privacy Policy

When you participate in a CME activity offered by CMEducation Resources, we request your name, degree, affiliation, street address, telephone number, fax number, and/or e-mail address (the "Information"). We use that Information in the following ways:

  • We use the Information to grade your post-test and to send you a certificate of completion of the CME activity.
  • We may use the Information to send you information about other CME activities that CMEducation Resources is offering.
  • CMEducation Resources may use the information to offer you additional CME activities from other organizations, but will not release your information to a third party for any promotional purposes.

Disclaimer:

Copyright © 2011 Resources, LLC All rights reserved.

Reproduction, distribution, or translation without express written permission is strictly prohibited.

Content on this webcast reflects the opinions, output, and analyses of experts, investigators, educators, and clinicians whose activities for, while independent, are commercially supported by the sponsor noted at the start of each activity.

Content on this webcast is not meant to be, nor substitute for national guidelines or recommendations generated by professional, academic societies, colleges, or associations.

Content on this webcast is intended for educational value only. Its contents, analyses, and any recommendation made herein are intended to make scientific information and opinion available to health professionals, to stimulate thought, and further investigation. This webcast is not designed nor is any aspect of the contents here intended to provide advice regarding medical diagnosis or treatment for any individual case. Any decisions regarding diagnosis and/or management of any individual patient or group of patients should be made on individual basis after having consulted appropriate sources, whether they be appropriate consultants and/or guidelines and recommendations issued by national organizations, professional societies, governmental health organizations, or similar bodies. This webcast is not intended for use by the layman.

Opinions expressed herein are not necessarily those of CMEducation Resources, LLC, program supporters or accreditors, but reflect the opinions and analyses of the experts who have authored the material. Mention of products or services does not constitute endorsement. Clinical, legal, financial, and other comments are offered for general guidance only; and professional counsel should be sought for all specific situations.

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Copyright © 2011 Resources, LLC All rights reserved.

 
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Key Program Topics Include:

ACCESS Trial
antibiotics
APACHE II
Apoptosis
Biglycans
E5564
Endotoxemia
Talactoferrin

Endotoxin in Critically Ill
Epitopes
Eritoran
Fibronectin
HMGB1
Hyaluronan
hypotension
Immune Modulation

 

immunosuppression
Inflammatory Cascade
IRAK-4
LPS
lymphocytes
Multicentric, randomized, double-blind trial
Polymyxin B
Sepsis
Serum lactate
Signalsome
TAK-242
TLR
Pyogenic
TLR4 Ligands
Toll like receptor
Toll-like receptor