NOAC-Based Stroke Prevention in AF and Management of ACS


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Webcast CME Disclosure

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Program Medium

Internet-based program

Estimated Time to Complete Educational Activity

1.0 hours

Course Overview

In this web-based program, physicians will learn how recent advances in basic and clinical research have helped to advance the understanding of treatment advances in venous thromboembolism.

Release Date

September 24, 2015

Expiration Date

September 24, 2017

Method of Physician Participation Utilized in Learning Process

There are no fees for participating and receiving CME credit for this activity. During the period September 24, 2015 through September 24, 2017, participants must 1) read the learning objectives and faculty disclosures; 2) study the educational activity, and are expected to view all 4 segments totaling 1.0 hours to successfully complete the activity and earn CME credit; 3) register and complete the evaluation form and post-test; 4) score 100% on the post-test; and 5) print out your CME certificate.


Participation in this WebCAST is complimentary, and clinicians are invited to view this CME-certified program and/or share this invitation with other colleagues, departmental staff members, and healthcare professionals.

Grantor Support

Supported by an educational grant from Bayer Pharma AG.

Accreditation Statement

This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the University of Massachusetts Medical School and CMEducation Resources, LLC. The University of Massachusetts Medical School is accredited by the ACCME to provide continuing medical education for physicians.

Credit Designation Statement

The University of Massachusetts Medical School designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credits(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Policy on Faculty & Provider Disclosure

It is the policy of the University of Massachusetts Medical School to ensure fair balance, independence, objectivity and scientific rigor in all activities. All faculty participating in CME activities sponsored by the University of Massachusetts Medical School are required to present evidence-based data, identify and reference off-label product use and disclose all relevant financial relationships with those supporting the activity or others whose products or services are discussed. Faculty disclosure will be provided in the activity materials.

Other Credits

American Nurses Credentialing Center (ANCC) accepts AMA PRA Category 1 Credits™ from organizations accredited by the ACCME.
American Academy of Nurse Practitioners (AANP) accepts AMA PRA Category 1 Credits™ from organizations accredited by the ACCME.
American Academy of Physician Assistants (AAPA) accepts certificates of participation for educational activities certified for AMA PRA Category 1 Credits™ from organizations accredited by the ACCME.

Program Faculty and Disclosure

Samuel Z. Goldhaber, MD
Program Co-Chair
Professor of Medicine
Harvard Medical School
Director, Thrombosis Research Group, Director, Vascular Center
Brigham and Women’s Hospital
Boston, Massachusetts

Consultant: Boehringer-Ingelheim, BMS, Daiichi, Janssen, Portola
Grant/Research Support: BMS, BTG, Daiichi, NHLBI, Thrombosis Research Institute, BIO² Medical

Professor The Lord Ajay Kakkar, BSc, PhD, FRCS
Program Co-Chair
Professor of Surgery
University College London
London, UK

Consultant: Armetheon Inc., Aspen Pharmacare, Bayer Pharma, Boehringer Ingelheim Pharma, Daiichi Sankyo Europe, Sanofi S.A.
Grant/Research Support: Armetheon Inc, Bayer Pharma

Professor of Cardiology
Head of Research, Div. of Medicine
Oslo University Hospital, Ullevål
Oslo, Norway

Steering Committee member, National Coordinator for Norway, and Co-author of ACTIVE, ARISTOTLE, AVERROES, GARFIELD, ENGAGE-AF, XANTUS, RE-ALIGN, RE-VERSE, EVOLVE-AF, ARTESIA, PLATO.
Fees, honoraria from Boehringer- Ingelheim, Bayer, BMS/Pfizer, Daiichi-Sankyo, Nycomed-Takeda, Cardiome, Astra-Zeneca, MSD

Philippe Gabriel Steg, MD, FESC, FACC
Director, Coronary Care Unit
Hôpital Bichat
Professor of Cardiology
University Paris VII
Paris, France

Research grants (to INSERM U1148): Servier, Sanofi
Speaker or consultant (including steering committee, DMC and CEC memberships): Amarin, AstraZeneca, Bayer, Boehringer-Ingelheim, BristolMyersSquibb, CSL-Behring, Daiichi-Sankyo-Lilly, GlaxoSmithKline, Janssen, Medtronic, Merck-Sharpe Dohme, Novartis, Pfizer, Regeneron, Sanofi, Servier, The Medicines Company
Stockholder: Aterovax

Program Managers and Web Editor Disclosure

Program Manager Gideon Bosker, MD has nothing to disclose.
Program Reviewer Denise Leary has nothing to disclose.

Educational Objectives

Upon completion of this activity, participants will be able to:

  • Explain the role of compliance and regimen adherence forstroke prevention in AF; and the potential advantages of once-daily administration to improve long-term compliance;
  • Optimally use oral factor Xa inhibitors in real world patients with AF and ACS based on real world experience, clinical trial results, registry data, and ESC guidelines;
  • Risk-stratify patients with non-valvular AF, with a focus on the CHA2DS2-VASc and HAS-BLED risk scores that currently are recommended to guide anticoagulation management in AF;
  • Employ factor Xa inhibition for stroke prevention in high risk patients with AF, including those with a previous TIA or stroke;
  • Select appropriate patients with ACS who can benefit from oral factor Xa inhibition to safely and effectively reduce the risk of recurrent MI in the setting of ACS.

Hardware and Software Requirements:

To participate in this program, viewers must have a PC or Macintosh computer that has active, ongoing internet access for the duration of the program, as well as a compatible Flash-viewer. An email address is required for registration, and a printer is required to print out the CME certificate.

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When you participate in a CME activity offered by CMEducation Resources, we ask you for your name, degree, affiliation, street address, telephone number, fax number, and/or e-mail address (the "Information"). We use that Information in the following ways:

  • We use the Information to grade your post-test and to send you a certificate of completion of the CME activity. If we use a third-party company to grade your post-test and issue certificates of completion, we will give the Information to that company for that purpose only.
  • For each CME activity that you take, you must complete an evaluation questionnaire. That questionnaire asks if you are willing to participate in a follow-up survey. If you answer yes, we will use your name and contact information to send you the survey.
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Content on this webcast reflects the opinions, output, and analyses of experts, investigators, educators, and clinicians whose activities for, while independent, are commercially supported by the sponsor noted at the start of each activity.

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Key Program Topics Include:

ACC/AHA/ESC Guidelines

Atrial Fibrillation


Factor Xa Inhibitor
Intracerebral Hemorrhage
Myocardial infarction
Pulmonary embolism

RE-LY Trial
rhythm control
Valvular Atrial Fibrillation